Hydroxychloroquine Tablets 200 mg

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Why is this medication prescribed?
Hydroxychloroquine is used to prevent and treat acute attacks of malaria. It is also used to treat discoid lupus erythematosus (DLE; a chronic inflammatory condition of the skin) or systemic lupus erythematosus (SLE; a chronic inflammatory condition of the body) and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Hydroxychloroquine is in a class of drugs called antimalarials. It works by killing the organisms that cause malaria. Hydroxychloroquine may work to treat rheumatoid arthritis and systemic lupus erythematosus by decreasing the activity of the immune system.

How should this medicine be used?
Hydroxychloroquine comes as a tablet to take by mouth. If you are an adult and taking hydroxychloroquine to prevent malaria, one dose is usually taken once a week on exactly the same day of each week. You will begin treatment 1 to 2 weeks before you travel to an area where malaria is common and then continue during your time in the area and for 4 weeks after you return. If you are an adult and taking hydroxychloroquine to treat malaria, the first dose is usually taken right away, followed by another dose 6 to 8 hours later and then additional doses on each of the next 2 days. For prevention or treatment of malaria in infants and children, the amount of hydroxychloroquine is based on the child’s weight. Your doctor will calculate this amount and tell you how much hydroxychloroquine your child should receive.

If you are taking hydroxychloroquine to treat lupus erythematosus (DLE or SLE), it is usually taken once or twice a day. If you are taking hydroxychloroquine to treat rheumatoid arthritis, it is usually taken once or twice a day.

Swallow the tablets whole; do not split, chew, or crush them.

Hydroxychloroquine tablets can be taken with a glass of milk or a meal to decrease nausea.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take hydroxychloroquine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you, do not stop taking hydroxychloroquine without talking to your doctor. Symptoms of rheumatoid arthritis will return if you stop taking hydroxychloroquine.

Other uses for this medicine
Hydroxychloroquine is used occasionally to treat porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?
Before taking hydroxychloroquine,
tell your doctor and pharmacist if you are allergic to hydroxychloroquine, chloroquine, primaquine, quinine, or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription drugs, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention acetaminophen (Tylenol, others); azithromycin (Zithromax); cimetidine (Tagamet); cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin), insulin and oral medication for diabetes; medications for seizures such as carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenytoin (Dilantin, Phenytek), or valproic acid (Depakene); certain medications for irregular heartbeat such as amiodarone (Pacerone); methotrexate (Trexall, Xatmep); moxifloxacin (Avelox); praziquantel (Biltricide); and tamoxifen (Nolvadex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with hydroxychloroquine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
if you are taking antacids, take them 4 hours before or 4 hours after hydroxychloroquine. If you are taking ampicillin, take it at least 2 hours before or 2 hours after hydroxychloroquine.
tell your doctor if you have or have ever had liver disease, heart disease, a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), an irregular heartbeat, a low level of magnesium or potassium in your blood, psoriasis, porphyria or other blood disorders, G-6-PD deficiency (an inherited blood disease), dermatitis (skin inflammations), seizures, vision problems, diabetes, kidney problems, or if you drink large amounts of alcohol.
tell your doctor if you have ever had vision changes while taking hydroxychloroquine, chloroquine (Aralen), or primaquine.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking hydroxychloroquine, call your doctor.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?
Hydroxychloroquine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
headache
dizziness
loss of appetite
nausea
diarrhea
stomach pain
vomiting
rash